Research article summary (published 29 Nov 1996):

Role of the hippocampus plus subjacent cortex but not amygdala in visuomotor conditional learning in rhesus monkeys.

Full Abstract

Rhesus monkeys were trained to learn a large series of visuomotor conditional associations, each involving the arbitrary coupling of a visual stimulus with 1 of 3 potentially correct forelimb movements. The monkeys then received bilateral aspiration lesions of either the amygdala plus subjacent cortex or the hippocampus plus subjacent cortex. Hippocampal but not amygdala removals significantly retarded the learning of new visuomotor associations. Neither lesion affected retention. The findings argue against a general role for the amygdala in associating information across modalities, construed broadly to include motor information. By contrast, the finding that the hippocampal formation and its subjacent cortex play a role in learning new sensorimotor associations supports the view that this region participates in the long-term storage of associative information or in the recall of recently acquired information.

Author information

Author/s: Murray, E A (EA); Wise, S P (SP);

Affiliation: Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, Maryland. eam(-atsign-)In.nimh.nih.gov

Journal and publication information

Publication Type: Journal Article

Journal: Behavioral neuroscience (Behav Neurosci), published in UNITED STATES. (Language: eng)

Reference: 1996-Dec; vol 110 (issue 6) : pp 1261-70

Dates: Created 1997/04/08; Completed 1997/04/08; Revised 2003/11/14;

PMID: 8986330, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MESH Headings shown below.

Amygdala - physiology Animals Association Learning - physiology Cerebral Cortex - physiology Hippocampus - physiology Macaca mulatta

Macaca mulatta Male Memory - physiology Motor Activity - physiology Retention (Psychology) - physiology Visual Perception - physiology

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