Circadian rhythm, sleep, and epilepsy.

Full Abstract

This review article: (1) describes the circadian distribution of ictal and interictal events; (2) differentiates transitional arousal, non-rapid eye movement and rapid eye movement sleep components and their substrates; (3) suggests the means by which the neural generators of these seizure-prone vs. seizure-resistant sleep and arousal states modulate the timing of different seizure manifestations; (4) considers clinical and mechanistic findings for the reciprocal effects of seizures and antiepileptic drugs upon the sleep-wake cycle; and (5) assesses clinical and basic mechanisms of sleep deprivation effects upon seizures.

Author information

Author/s: Shouse, M N (MN); da Silva, A M (AM); Sammaritano, M (M);

Affiliation: Sleep Disturbance Research, VAMC, Sepulveda, California, USA.

Journal and publication information

Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Review

Journal: Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society (J Clin Neurophysiol), published in UNITED STATES. (Language: eng)

Reference: 1996-Jan; vol 13 (issue 1) : pp 32-50

Dates: Created 1997/02/07; Completed 1997/02/07; Revised 2006/11/15;

PMID: 8988284, status: MEDLINE (last retrieved date: 2/18/2009)

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