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| Research article summary (published 29 Sep 1998): |
Improvement of P300 latency by treatment in non-insulin-dependent diabetes mellitus.
Full Abstract
P300 event-related potentials were investigated in 24 cases of non-insulin-dependent (Type II) diabetes mellitus (NIDDM) without apparent central nervous system (CNS) symptoms and without cerebrovascular diseases on head magnetic resonance imaging, and in 16 age-matched healthy control subjects. N200 and P300 latencies were significantly prolonged and N200 and P300 amplitudes were significantly smaller in the NIDDM group than in the healthy control group. P300 latency was significantly shorter after the treatment than before. N200 and P300 waves have been recognized as useful indicators of cognitive function. The present study suggests that cognitive function is impaired in NIDDM patients and may improve with treatment of hyperglycemia.
Author information
Author/s: Mochizuki, Y (Y); Oishi, M (M); Hayakawa, Y (Y); Matsuzaki, M (M); Takasu, T (T);
Affiliation: Department of Neurology, Nihon University School of Medicine, Tokyo, Japan.
Journal and publication information
Publication Type: Journal Article
Journal: Clinical EEG (electroencephalography) (Clin Electroencephalogr), published in UNITED STATES. (Language: eng)
Reference: 1998-Oct; vol 29 (issue 4) : pp 194-6
Dates: Created 1998/12/16; Completed 1998/12/16; Revised 2004/11/17;
PMID: 9783095, status: MEDLINE (last retrieval date: 2/18/2009, IMS Date: )
Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.
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