Research article summary (published 24 Nov 1976):

[Creatinine during pregnancy (author's transl)]

(Kreatinin in der Schwangerschaft)

Full Abstract

Determination of the creatinine concentration of the amniotic fluid was undertaken between the 25th and 40th week of gestation in 114 patients. The normal serum creatinine level was simultaneously determined in 43 of these patients. The aim of this study was to examine whether this parameter of fetal renal function allows a conclusion to be drawn with respect to fetal maturity and the length of gestation. With increasing length of gestation a marked increase in the amniotic fluid and the maternal serum creatinine concentration was observed (p less than 0.01). The large scatter of the values made it impossible to relate any particular creatinine concentration to a certain week of gestation. However, if the concentration of creatinine in the amniotic fluid has reached a value of 2 mg% or more, a mature baby can be predicted in most cases. A tendency to raised levels of creatinine was seen in cases of EPH gestosis and latent diabetes mellitus. The determination of creatinine in the amniotic fluid can be recommended with certain reservations as an additional method to assess fetal maturity.

Author information

Author/s: Gitsch, E (E);

Journal and publication information

Publication Type: English Abstract; Journal Article

Journal: Wiener klinische Wochenschrift (Wien Klin Wochenschr), published in AUSTRIA. (Language: ger)

Reference: 1976-Nov; vol 88 (issue 22) : pp 740-2

Dates: Created 1977/01/25; Completed 1977/01/25; Revised 2006/11/15;

PMID: 997551, status: MEDLINE (last retrieved date: 2/18/2009)

Sourced from the National Library of Medicine. Abstract text and other information may be subject to copyright.

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MeSH headings (categories)

This article was linked to the MeSH Headings (categories) shown below.

Amniotic Fluid - metabolism Creatinine - blood; metabolism Female Fetus - physiology Gestational Age

Gestational Age Humans Pre-Eclampsia - blood Pregnancy Pregnancy in Diabetics - blood

Note: Bold headings indicate primary MeSH headings or qualifiers.

Associated Chemicals: Creatinine (60-27-5)

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